10.1371/journal.pgen.1008586.g008 Takeshi Moriishi Takeshi Moriishi Ryosuke Ozasa Ryosuke Ozasa Takuya Ishimoto Takuya Ishimoto Takayoshi Nakano Takayoshi Nakano Tomoka Hasegawa Tomoka Hasegawa Toshihiro Miyazaki Toshihiro Miyazaki Wenguang Liu Wenguang Liu Ryo Fukuyama Ryo Fukuyama Yuying Wang Yuying Wang Hisato Komori Hisato Komori Xin Qin Xin Qin Norio Amizuka Norio Amizuka Toshihisa Komori Toshihisa Komori Body weight, blood glucose, HbA1c, and adipose tissues in Ocn<sup>–/–</sup>mice. Public Library of Science 2020 Ocn strength BAp testosterone synthesis collagen fibrils muscle mass crystallite bone quantity glucose metabolism 2020-05-28 17:25:14 Figure https://plos.figshare.com/articles/figure/Body_weight_blood_glucose_HbA1c_and_adipose_tissues_in_Ocn_sup__sup_mice_/12384446 <p>(A)Body weights of male (m) and female (f) wild-type and Ocn<sup>–/–</sup>mice. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6), female (n = 9, 6) at 11w; male (n = 25, 18) at 14w; male (n = 14, 23), female (n = 6, 8) at 6m; male (n = 7, 9), female (n = 8, 12) at 9m; female (n = 8, 6) at 12m; male (n = 7, 4) at 18m. (B) Blood glucose levels. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6) at 14w; male (n = 16, 16), female (n = 8, 13) at 9m; male (n = 7, 5) at 18m. (C) HbA1c levels. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6), female (n = 9, 10) at 11w; male (n = 14, 18), female (n = 6, 7) at 6m; male (n = 9, 7), female (n = 9, 13) at 9m; male (n = 7, 5) at 18m. (D-H) Measurement of adipose tissues. D-G, Sagittal sections at the midline (D, E) and cross sections at the level of L5 (F, G) of μ-CT in male mice at 14 weeks of age. Subcutaneous adipose tissues are shown orange and visceral adipose tissues are shown yellow in the range of the first to fifth vertebra. H, Volumes of subcutaneous and visceral adipose tissues in wild-type (n = 10) and Ocn<sup>–/–</sup>(n = 6) male mice at 14 weeks of age and wild-type (n = 8) and Ocn<sup>–/–</sup>(n = 5) female mice at 9 months of age. The percentages of adipose tissue volumes against abdominal volumes in the range of the first to fifth vertebra are shown. X symbols in box plots show outliers.</p>