10.1371/journal.pgen.1008586.g008
Takeshi Moriishi
Takeshi
Moriishi
Ryosuke Ozasa
Ryosuke
Ozasa
Takuya Ishimoto
Takuya
Ishimoto
Takayoshi Nakano
Takayoshi
Nakano
Tomoka Hasegawa
Tomoka
Hasegawa
Toshihiro Miyazaki
Toshihiro
Miyazaki
Wenguang Liu
Wenguang
Liu
Ryo Fukuyama
Ryo
Fukuyama
Yuying Wang
Yuying
Wang
Hisato Komori
Hisato
Komori
Xin Qin
Xin
Qin
Norio Amizuka
Norio
Amizuka
Toshihisa Komori
Toshihisa
Komori
Body weight, blood glucose, HbA1c, and adipose tissues in Ocn<sup>–/–</sup>mice.
Public Library of Science
2020
Ocn
strength
BAp
testosterone synthesis
collagen fibrils
muscle mass
crystallite
bone quantity
glucose metabolism
2020-05-28 17:25:14
Figure
https://plos.figshare.com/articles/figure/Body_weight_blood_glucose_HbA1c_and_adipose_tissues_in_Ocn_sup__sup_mice_/12384446
<p>(A)Body weights of male (m) and female (f) wild-type and Ocn<sup>–/–</sup>mice. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6), female (n = 9, 6) at 11w; male (n = 25, 18) at 14w; male (n = 14, 23), female (n = 6, 8) at 6m; male (n = 7, 9), female (n = 8, 12) at 9m; female (n = 8, 6) at 12m; male (n = 7, 4) at 18m. (B) Blood glucose levels. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6) at 14w; male (n = 16, 16), female (n = 8, 13) at 9m; male (n = 7, 5) at 18m. (C) HbA1c levels. Male (wt: n = 5, Ocn<sup>–/–</sup>: n = 6), female (n = 9, 10) at 11w; male (n = 14, 18), female (n = 6, 7) at 6m; male (n = 9, 7), female (n = 9, 13) at 9m; male (n = 7, 5) at 18m. (D-H) Measurement of adipose tissues. D-G, Sagittal sections at the midline (D, E) and cross sections at the level of L5 (F, G) of μ-CT in male mice at 14 weeks of age. Subcutaneous adipose tissues are shown orange and visceral adipose tissues are shown yellow in the range of the first to fifth vertebra. H, Volumes of subcutaneous and visceral adipose tissues in wild-type (n = 10) and Ocn<sup>–/–</sup>(n = 6) male mice at 14 weeks of age and wild-type (n = 8) and Ocn<sup>–/–</sup>(n = 5) female mice at 9 months of age. The percentages of adipose tissue volumes against abdominal volumes in the range of the first to fifth vertebra are shown. X symbols in box plots show outliers.</p>