%0 Figure %A Choi, Jang-Hoon %A Woo, Hye-Min %A Lee, Tae-young %A Lee, So-young %A Shim, Sang-Mu %A Park, Woo-Jung %A Yang, Jeong-Sun %A Kim, Joo Ae %A Yun, Mi-Ran %A Kim, Dae-Won %A Kim, Sung Soon %A Zhang, Yi %A Shi, Wei %A Wang, Lingshu %A Graham, Barney S. %A Mascola, John R. %A Wang, Nanshuang %A McLellan, Jason S. %A Lee, Joo-Yeon %A Lee, Hansaem %D 2020 %T Determination of 50% mouse lethal dose (LD50). %U https://plos.figshare.com/articles/figure/Determination_of_50_mouse_lethal_dose_LD_sub_50_sub_/12274418 %R 10.1371/journal.pone.0232757.s002 %2 https://plos.figshare.com/ndownloader/files/22615238 %K syndrome coronavirus Middle East %K prefusion-stabilized spike protein %K B cells %K receptor-binding domain %K RBD-specific antibodies %K PBMC %K syndrome coronavirus %K S 1 %K IC %K prefusion MERS-CoV S probe %K KNIH 90-F %K neutralizing potency %K DPP 4 %K antibody %X

(A) Body weight loss curve of 10-week-old male C57BL/6N-hDPP4 mice (n = 5 per group) infected with different doses of MERS-CoV KNIH-002. The error bar indicate the standard error of the mean. The weight loss and survival were monitored for 14 days.

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%I PLOS ONE