Determination of 50% mouse lethal dose (LD<sub>50</sub>). Jang-Hoon Choi Hye-Min Woo Tae-young Lee So-young Lee Sang-Mu Shim Woo-Jung Park Jeong-Sun Yang Joo Ae Kim Mi-Ran Yun Dae-Won Kim Sung Soon Kim Yi Zhang Wei Shi Lingshu Wang Barney S. Graham John R. Mascola Nanshuang Wang Jason S. McLellan Joo-Yeon Lee Hansaem Lee 10.1371/journal.pone.0232757.s002 https://plos.figshare.com/articles/figure/Determination_of_50_mouse_lethal_dose_LD_sub_50_sub_/12274418 <p>(A) Body weight loss curve of 10-week-old male C57BL/6N-hDPP4 mice (n = 5 per group) infected with different doses of MERS-CoV KNIH-002. The error bar indicate the standard error of the mean. The weight loss and survival were monitored for 14 days.</p> <p>(TIF)</p> 2020-05-08 17:30:46 syndrome coronavirus Middle East prefusion-stabilized spike protein B cells receptor-binding domain RBD-specific antibodies PBMC syndrome coronavirus S 1 IC prefusion MERS-CoV S probe KNIH 90-F neutralizing potency DPP 4 antibody