Simulated population fitness under different levels of pleiotropy, i.e. the number of phenotypes controlled by a single QTL (horizontal axis). Tuomas Hämälä Amanda J. Gorton David A. Moeller Peter Tiffin 10.1371/journal.pgen.1008707.g005 https://plos.figshare.com/articles/figure/Simulated_population_fitness_under_different_levels_of_pleiotropy_i_e_the_number_of_phenotypes_controlled_by_a_single_QTL_horizontal_axis_/12032055 <p>Phenotypes start from an initial value 0 and selection acts to move them towards three different optima. Shown are medians and interquartile ranges (IQR) from 300 simulation. The fitness estimates were normalized in relation to the non-pleiotropic class (median = 0, IQR = 1).</p> 2020-03-25 17:33:56 pleiotropic adaptation populations face novel phenotype ragweed allele optima gene networks artemisiifolia connectivity trait evolution states Pleiotropy putatively adaptive loci human-mediated habitat change use genotype-expression mapping Ambrosia North American range pleiotropy