Overlap statistic maxR for DEG and WAP scores as a function of MVT p-values.
Joël R. Pradines
Victor Farutin
Nicholas A. Cilfone
Abouzar Ghavami
Elma Kurtagic
Jamey Guess
Anthony M. Manning
Ishan Capila
10.1371/journal.pcbi.1007684.g008
https://plos.figshare.com/articles/Overlap_statistic_maxR_for_DEG_and_WAP_scores_as_a_function_of_MVT_p-values_/11857407
<p>A-B: Overlap statistic maxR for DEG and WAP scores as a function of MVT p-values in each data set of a simulated pair. C: Difference of maxR statistic (WAP minus DEG) as a function of MVT p-values in each data set of a simulated pair. D: Difference of maxR statistic (WAP minus DEG) as a function of MVT p-value in one data set and average WAP p-value in the other. Plots summarize results obtained with 2 × 10<sup>5</sup> random partitions of GSE58095.</p>
2020-02-14 18:33:32
concept
data sets
precision medicine studies
protein interaction networks
gene expression data
prioritize novel targets
DEG
gene expression analysis
discovery rate estimation
well-associated protein Identification
WAP
genome-wide transcriptional studies
reproducibility
drug target selection