%0 Figure %A Pradines, Joël R. %A Farutin, Victor %A Cilfone, Nicholas A. %A Ghavami, Abouzar %A Kurtagic, Elma %A Guess, Jamey %A Manning, Anthony M. %A Capila, Ishan %D 2020 %T Illustrations of overlap profiles. %U https://plos.figshare.com/articles/figure/Illustrations_of_overlap_profiles_/11857389 %R 10.1371/journal.pcbi.1007684.g003 %2 https://plos.figshare.com/ndownloader/files/21731709 %K concept %K data sets %K precision medicine studies %K protein interaction networks %K gene expression data %K prioritize novel targets %K DEG %K gene expression analysis %K discovery rate estimation %K well-associated protein Identification %K WAP %K genome-wide transcriptional studies %K reproducibility %K drug target selection %X

A: Overlap profiles of WAP (blue) and DEG (green) scores across two gene expression data sets, where skin samples of SSc patients are compared to samples of non-SSc subjects. Values of and indicate sizes of gene sets and intersection between them corresponding to maxR values for WAP and DEG score profiles. B: The two summary statistics of an overlap profile.

%I PLOS Computational Biology