Soong, Lynn Wang, Hui R. Shelite, Thomas Liang, Yuejin L. Mendell, Nicole Sun, Jiaren Gong, Bin A. Valbuena, Gustavo H. Bouyer, Donald H. Walker, David Endothelial cell activation and stress in the liver and lungs. <p>Mice (4–5/group) were inoculated with <i>O. tsutsugamushi</i> Karp stain, as described in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003191#pntd-0003191-g001" target="_blank"><b><i>Fig. 1</i></b></a>. Liver and lung tissues were collected at 0, 2, 6, and 10 dpi and analyzed via qRT-PCR for gene expression. (<b>A, C</b>) Data are shown as mean ± SEM in each group and are presented as “relative mRNA level” (after normalization to the housekeeping genes). (<b>B, D</b>) The Ang-2/Ang-1 ratios of individual samples were calculated based on the corresponding data in <b>A</b> and <b>C</b>. *, <i>p</i><0.05; **, <i>p</i><0.01.</p> typhus;disease pathogenesis;inoculated C 57BL mice;alteration;murine model;obligately intracellular;ifn;ror;gata;tsutsugamushi infection;mpo;cxcr;cxcl;Orientia tsutsugamushi;animal death;Growth factors;tissue damage;tnf;il 2014-09-25
    https://plos.figshare.com/articles/figure/_Endothelial_cell_activation_and_stress_in_the_liver_and_lungs_/1182377
10.1371/journal.pntd.0003191.g007