Binding of diosgenin to α-glucosidase active pocket.
Sougata Ghosh
Piyush More
Abhishek Derle
Ajay B. Patil
Pramod Markad
Adersh Asok
Navanath Kumbhar
Mahemud L. Shaikh
Boppana Ramanamurthy
Vaishali S. Shinde
Dilip D. Dhavale
Balu A. Chopade
10.1371/journal.pone.0106039.g010
https://plos.figshare.com/articles/figure/_Binding_of_diosgenin_to_945_glucosidase_active_pocket_/1169373
<p>(a) Depicts docked conformation of diosgenin with yeast alpha glucosidase (3AXI.pdb), (b) hydrogen bonding and hydrophobic interactions from alpha glucosidase-diosgenin inhibitor complex.</p>
2014-09-12 02:48:36
type II diabetes mellitus
diosgenin
ftir
hplc
glucosidase
1 H NMR
PPHG
Gln 63 residues
amylase
Dioscorea bulbifera
ethyl acetate
novel drug candidate
13 C NMR