The groups in the presented study. Markus L. Schwarz Gregor Reisig Andy Schütte Kristianna Becker Susanne Serba Elmar Forsch Steffen Thier Stefan Fickert Tamara Lenz Christel Weiß Svetlana Hetjens Frederic Bludau Friederike Bothe Wiltrud Richter Barbara Schneider-Wald 10.1371/journal.pone.0224996.t001 https://plos.figshare.com/articles/dataset/The_groups_in_the_presented_study_/11463411 <p>Two healing periods for the treated animals were assessed, one of approximately half a year (24 weeks) and the other of approximately one year (48 weeks). The NAT group consisted of animals that received no surgical treatment; their articular cartilage served as an “external control”. The groups with animals in which matrices made out of Col 1 were implanted without cells (M24w and M48w) can be interpreted as verum or control groups for the cell loaded implants (MC24w and MC48w). The groups with empty defects (E24w and E48w) can be seen as control for the groups with implants as well as control for the animal model in terms of the critical size of the created defects.</p> 2019-12-26 18:34:37 3 R requirements NAT 1 year animal model ES histological results Spontaneous regenerated AC G öttingen Minipig regenerated articular cartilage 1 st operation