10.1371/journal.pone.0224996.g011 Markus L. Schwarz Markus L. Schwarz Gregor Reisig Gregor Reisig Andy Schütte Andy Schütte Kristianna Becker Kristianna Becker Susanne Serba Susanne Serba Elmar Forsch Elmar Forsch Steffen Thier Steffen Thier Stefan Fickert Stefan Fickert Tamara Lenz Tamara Lenz Christel Weiß Christel Weiß Svetlana Hetjens Svetlana Hetjens Frederic Bludau Frederic Bludau Friederike Bothe Friederike Bothe Wiltrud Richter Wiltrud Richter Barbara Schneider-Wald Barbara Schneider-Wald The condyles were examined as remote regions to the trochleae were the defects were created. Public Library of Science 2019 3 R requirements NAT 1 year animal model ES histological results Spontaneous regenerated AC G öttingen Minipig regenerated articular cartilage 1 st operation 2019-12-26 18:34:36 Figure https://plos.figshare.com/articles/figure/The_condyles_were_examined_as_remote_regions_to_the_trochleae_were_the_defects_were_created_/11463408 <p>Surprisingly, the NAT group revealed the worst condition of the articular cartilage of all groups. Two treated groups were actually significantly better. The results show that in this age group the GM can develop degenerative changes at the condyles rather than at the trochleae (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0224996#pone.0224996.g010" target="_blank">Fig 10</a>).</p>