Induction of KLF6 splice variants by simvastatin. Emma Hennessy Julie O'Callaghan Marlies J. Mooij Claire Legendre Olga Camacho-Vanegas Sandra C. Camacho Claire Adams John A. Martignetti Fergal O'Gara 10.1371/journal.pone.0102200.g002 https://plos.figshare.com/articles/figure/_Induction_of_KLF6_splice_variants_by_simvastatin_/1099268 <p>A549 cells were treated with 10 µM simvastatin for 24 hours, following which they were infected with <i>P. aeruginosa</i> PAO1 for 3 hours at MOI 50∶1. The expression of (<b>A</b>) SV1, (<b>B</b>) SV2 and (<b>C</b>) SV3 was examined using qRT-PCR. *<i>P</i>, ≤0.05, **<i>P</i>, ≤0.01.</p> 2014-07-10 02:59:17 cell biology Molecular cell biology genetics gene expression immunology Immune response inflammation Immune system Innate immune system immunity Immune activation microbiology bacteriology Gram negative bacteria Medical microbiology Microbial pathogens Bacterial pathogens Infectious diseases Bacterial diseases Pseudomonas infections Pathology and laboratory medicine pathogenesis Host-pathogen interactions klf6 splice variants