Fujimaki, Takahiro Saiki, Shinji Tashiro, Etsu Yamada, Daisuke Kitagawa, Mitsuhiro Hattori, Nobutaka Imoto, Masaya Licopyranocoumarin and glycyrurol prevented MPP<sup>+</sup>-induced cell death. <p>Structures of (<b>A</b>) licopyranocoumarin (LPC) and (<b>B</b>) glycyrurol (GCR). (<b>C</b>) NGF-differentiated PC12D cells were treated with various concentrations of LPC or GCR in the presence of 0.3 mM MPP<sup>+</sup> for 48 h. Cell viability was evaluated by trypan blue dye exclusion assay. (<b>D</b>) PC12D cells were treated with various concentration of LPC or GCR in the presence of 10 ng/ml taxol or 10 µg/ml cisplatin (CDDP) for 48 h. Values are the means of three independent experiments; bars, s.d. <sup>**</sup><i>p</i><0.01 compared with MPP<sup>+</sup> group cells.</p> Biochemistry;Neurochemistry;neuromodulation;antioxidants;chemical biology;Complementary and alternative medicine;Herbal medicine;glycyrurol;prevented 2014-06-24
    https://plos.figshare.com/articles/figure/_Licopyranocoumarin_and_glycyrurol_prevented_MPP_induced_cell_death_/1082179
10.1371/journal.pone.0100395.g003