Fujimaki, Takahiro Saiki, Shinji Tashiro, Etsu Yamada, Daisuke Kitagawa, Mitsuhiro Hattori, Nobutaka Imoto, Masaya Two herbal medicines, <i>daio-kanzo-to</i> and <i>choi-joki-to</i>, identified as neuroprotective agents in the course of screening. <p>(<b>A</b>) NGF-differentiated PC12D cells were treated with 0.3 µM rotenone and herbal medicine extract for 48 h. Cell viability was evaluated by trypan blue dye exclusion assay. (<b>B</b>) NGF-differentiated PC12D cells were treated with various concentrations of <i>choi-joki-to</i> or <i>daio-kanzo-to</i> in the presence of 0.3 mM MPP<sup>+</sup> for 48 h. Cell viability was evaluated by trypan blue dye exclusion assay. Values are the means of triplicate samples; bars, s.d. <sup>**</sup><i>p</i><0.01 compared with MPP<sup>+</sup> group cells.</p> Biochemistry;Neurochemistry;neuromodulation;antioxidants;chemical biology;Complementary and alternative medicine;Herbal medicine;herbal;neuroprotective;agents 2014-06-24
    https://plos.figshare.com/articles/figure/_Two_herbal_medicines_daio_kanzo_to_and_choi_joki_to_identified_as_neuroprotective_agents_in_the_course_of_screening_/1082176
10.1371/journal.pone.0100395.g001