Mutation of HPV16 L1 C161, C229, and C379 negatively impact virus infectivity. Eric J. Ryndock Michael J. Conway Samina Alam Sana Gul Sheeba Murad Neil D. Christensen Craig Meyers 10.1371/journal.pone.0099488.g003 https://plos.figshare.com/articles/figure/_Mutation_of_HPV16_L1_C161_C229_and_C379_negatively_impact_virus_infectivity_/1054158 <p>Relative levels of the E1∧E4 spliced transcript were measured by RT-qPCR in HaCaT cells 48 hours post-infection at an equal MOI (MOI = 5) for virus harvested from both 10- and 20-day tissues.</p> 2014-06-11 03:04:41 Evolutionary biology Organismal evolution Microbial evolution Viral evolution microbiology Virology Viral structure Viral transmission and infection Viruses and cancer hpv16 l1 c379 negatively