10.1371/journal.pone.0098464.t002
John N. Hutchinson
John
N. Hutchinson
Towfique Raj
Towfique
Raj
Jes Fagerness
Jes
Fagerness
Eli Stahl
Eli
Stahl
Fernando T. Viloria
Fernando
T. Viloria
Alexander Gimelbrant
Alexander
Gimelbrant
Johanna Seddon
Johanna
Seddon
Mark Daly
Mark
Daly
Andrew Chess
Andrew
Chess
Robert Plenge
Robert
Plenge
Confirmation of ASM in a subset of candidate cis-regulated ASM variants.
Public Library of Science
2014
Biochemistry
dna
DNA modification
Computational biology
genome analysis
Genome-wide association studies
genetics
gene expression
Gene regulation
genomics
Functional genomics
Human genetics
Genetic association studies
epigenetics
Genetics of disease
immunology
Clinical immunology
Autoimmune diseases
Genetics of the immune system
asm
subset
cis-regulated
2014-06-09 02:58:04
Dataset
https://plos.figshare.com/articles/dataset/_Confirmation_of_ASM_in_a_subset_of_candidate_cis_regulated_ASM_variants_/1050822
<p>Results from microarray and next-generation bisulfite sequencing ASM assays of ten variant-containing regions. The table shows the CpG position, whether it is found within an MSRE site and the Bonferroni adjusted chi-square based p-values of the association of methylation at this CpG with either the reference of alternate alleles. The allele with the highest number percentage of methylated reads was designated the most frequently methylated allele (REF = reference, ALT = alternate) and compared to that from the microarray data; for all CpGs that were within MSRE sites and showed significant association of methylation with an allele in the sequencing assay the methylated allele matched that of the microarray assay. For more details, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0098464#pone.0098464.s020" target="_blank">Table S3</a>.</p>