10.1371/journal.pone.0098165.g005
Nicholas S. Kirkby
Nicholas S.
Kirkby
Martina H. Lundberg
Martina
H. Lundberg
William R. Wright
William
R. Wright
Timothy D. Warner
Timothy
D. Warner
Mark J. Paul-Clark
Mark
J. Paul-Clark
Jane A. Mitchell
Jane
A. Mitchell
COX-2 deletion increases circulating levels of lymphocytes and lymphocyte-related cytokines in fat-fed apoE<sup>−/−</sup> mice.
Public Library of Science
2014
Computational biology
immunology
cardiology
Cardiovascular pharmacology
Clinical medicine
deletion
circulating
lymphocytes
lymphocyte-related
cytokines
fat-fed
2014-06-02 04:41:35
Figure
https://plos.figshare.com/articles/figure/_COX_2_deletion_increases_circulating_levels_of_lymphocytes_and_lymphocyte_related_cytokines_in_fat_fed_apoE_8722_8722_mice_/1042661
<p>Measurement of plasma levels of cytokines by multiplex immunoassay (a) demonstrated an increased in the lymphocyte-related cytokines IL-2 and IL-12 (total) and the neutrophil chemoattractant KC, but no change in levels of TNFα, IL-1β, IL-4, IL-10 or IFNγ. Cell counts in whole blood (b), measured in parallel, indicated an increase in circulating lymphocytes, but not monocytes, neutrophils or eosinophils. *; p<0.05 vs apoE<sup>−/−</sup>/COX-2<sup>+/+</sup> by unpaired t-test; n = 10–25.</p>