Genomes with Ku appear to fix GC alleles at a greater rate than expected (either due to BGC or selection). JL Weissman William F. Fagan Philip L. F. Johnson 10.1371/journal.pgen.1008493.g003 https://plos.figshare.com/articles/figure/Genomes_with_Ku_appear_to_fix_GC_alleles_at_a_greater_rate_than_expected_either_due_to_BGC_or_selection_/10277501 <p>(a,b) Genomes with Ku have, on average, even greater elevation of GC content over expectation than genomes without Ku. Expected GC content was estimated from polymorphism data. This signal is conservative due to observed polymorphisms experiencing some effects of BGC/selection (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008493#sec008" target="_blank">Methods</a> for discussion).</p> 2019-11-08 18:34:07 provide preliminary evidence dna damage may higher gc content double strand breaks strand breaks gc content selective adaptation remaining explanations relative importance reasons unknown prokaryotes near predicted solely particular habitats observed association observation suggests novel association gene conversion fundamental driver debate surrounds