10.1371/journal.pgen.1004302.g008
Sandra Tenreiro
Sandra
Tenreiro
Madalena M. Reimão-Pinto
Madalena
M. Reimão-Pinto
Pedro Antas
Pedro
Antas
José Rino
José
Rino
Donata Wawrzycka
Donata
Wawrzycka
Diana Macedo
Diana
Macedo
Rita Rosado-Ramos
Rita
Rosado-Ramos
Triana Amen
Triana
Amen
Meytal Waiss
Meytal
Waiss
Filipa Magalhães
Filipa
Magalhães
Andreia Gomes
Andreia
Gomes
Cláudia N. Santos
Cláudia
N. Santos
Daniel Kaganovich
Daniel
Kaganovich
Tiago Fleming Outeiro
Tiago
Fleming Outeiro
Inclusions formed by S129A aSyn-GFP are more heterogeneous than the ones formed by WT aSyn-GFP.
Public Library of Science
2014
neuroscience
Cellular neuroscience
Molecular neuroscience
Model organisms
Yeast and fungal models
formed
s129a
asyn-gfp
heterogeneous
ones
wt
2014-05-08 02:51:33
Figure
https://plos.figshare.com/articles/figure/_Inclusions_formed_by_S129A_aSyn_GFP_are_more_heterogeneous_than_the_ones_formed_by_WT_aSyn_GFP_/1020125
<p>(A) FRAP recovery curves for WT and S129A aSyn-GFP inclusions on yeast cells expressing aSyn forms at the indicated time points. For each strain, at least 15 inclusions in different cells were analyzed. Each plot represents mean ± SD for each time point for all FRAP experiments (for the WT aSyn-GFP expressing cells) or groups of FRAP experiments organized by recovery profiles (for the S129A aSyn-GFP expressing cells). (B) FRAP time lapse recording of a representative inclusion of each group (C) Area (pixels) and fluorescence intensity mean (in arbitrary units, a.u.) of the inclusions analyzed (***p<0.001 and ** p<0.01; one way ANOVA with Bonferroni's multiple comparison test). A representative result is shown from at least three independent experiments. Values represent the mean ± SD.</p>