10.1371/journal.pone.0096253.g003 Magali Saint-Geniez Magali Saint-Geniez Elisa Ghelfi Elisa Ghelfi Xiaoliang Liang Xiaoliang Liang Chenwei Yu Chenwei Yu Carrie Spencer Carrie Spencer Stephanie Abend Stephanie Abend Gokhan Hotamisligil Gokhan Hotamisligil Sule Cataltepe Sule Cataltepe Specific localization of FABP4 in neovascular endothelial cells. Public Library of Science 2014 anatomy biological tissue epithelium Epithelial cells Endothelial cells Cardiovascular anatomy Biochemistry lipids cell biology Cellular types Molecular cell biology developmental biology Organism development genetics gene expression cardiology ophthalmology Retinal disorders pediatrics Child development localization fabp4 neovascular endothelial 2014-05-06 02:57:11 Figure https://plos.figshare.com/articles/figure/_Specific_localization_of_FABP4_in_neovascular_endothelial_cells_/1017627 <p>(A) Confocal imaging of neovascular tufts in P17 WT OIR retina flat-mount following immunostaining for FABP4 (red), EC-specific marker EMCN (green), activated microglia-specific marker Iba1 (white) and DAPI (blue). FABP4 is strongly associated with the neovascular tufts and absent from the normal vasculature. FABP4 was not detected in the Iba1- positive cells but co-localized with EMCN-positive cells. (B) Immunostaining of FABP4 (red) EMCN (green) and DAPI (blue) in a large neovascular structure followed by confocal sectioning confirmed FABP4 localization to ECs of pathological neovessels. Scale bar is 50 µm.</p>